In this work, we study the gamma-ray shielding performance of a new glass composed of Al2O3, PbO2, SiO2, B2O3, and Gd2O3 with different mol% concentrations of Gd2O3 and PbO2. The glass sample’s densities, which increased from 4.18 to 4.36 g/cm3 for samples Al8Gd0.5 to Al8Gd2, were calculated via the Archimedes’ method. At the energy level of 0.015 MeV, the linear attenuation coefficient increased from 207.9 to 233.1 cm-1. At 0.06 MeV, the half-value layer of the produced glass samples fell by approximately 19.56%. The mean free path at 0.015 MeV reduced from 0.0048 to 0.0043 cm, whereas at the same energy range, the effective atomic number raised from 67.26 to 67.77, showing enhanced shielding performance when the concentration of Gd2O3 and PbO2 increased within the glass compositions. The results suggest that the Al8Gd2 glass is a promising candidate for radiation-shielding applications, particularly as protective windows in nuclear medicine and diagnostic imaging.